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CDH16 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR15392G 100 μl / $495

CDH16 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR15392G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDH16 antibody (C-term).

Molecular Weight

89923 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

796-824 aa

Target

This CDH16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 796-824 amino acids from the C-terminal region of human CDH16.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Summary

This gene is a member of the cadherin superfamily, genesencoding calcium-dependent, membrane-associated glycoproteins.Mapped to a previously identified cluster of cadherin genes onchromosome 16q22.1, the gene localizes with superfamily membersCDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of anextracellular domain containing 6 cadherin domains, a transmembraneregion and a truncated cytoplasmic domain but lacks the prosequenceand tripeptide HAV adhesion recognition sequence typical of mostclassical cadherins. Expression is exclusively in kidney, where theprotein functions as the principal mediator of homotypic cellularrecognition, playing a role in the morphogenic direction of tissuedevelopment.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Cadherin-16, Kidney-specific cadherin, Ksp-cadherin, CDH16

Images

CDH16 Antibody (C-term) (Cat. APR15392G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CDH16 antibody detected the CDH16 protein (arrow).

Specification

Quantity

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