> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > ARHGDIB Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR14308G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ARHGDIB antibody (C-term).
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Molecular Weight |
22988 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
160-188 aa
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Target |
This ARHGDIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-188 amino acids from the C-terminal region of human ARHGDIB.
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Isotype |
Rabbit Ig
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Symbol |
GDIA2, GDID4, RAP1GN1
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GeneID |
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UniProt ID |
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Function |
Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
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Summary |
Members of the Rho (or ARH) protein family (see MIM165390) and other Ras-related small GTP-binding proteins (see MIM179520) are involved in diverse cellular events, including cellsignaling, proliferation, cytoskeletal organization, and secretion.The GTP-binding proteins are active only in the GTP-bound state. Atleast 3 classes of proteins tightly regulate cycling between theGTP-bound and GDP-bound states: GTPase-activating proteins (GAPs),guanine nucleotide-releasing factors (GRFs), and GDP-dissociationinhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rateof GDP dissociation from Ras-like GTPases (summary by Scherle etal., 1993 [PubMed 8356058]).
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
Rho GDP-dissociation inhibitor 2, Rho GDI 2, Ly-GDI, Rho-GDI beta, ARHGDIB, GDIA2, GDID4, RAP1GN1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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