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UGDH Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR10653G 100 μl / $495

UGDH Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR10653G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UGDH antibody (C-term).

Molecular Weight

55024 Da

Host

Rabbit

Species Reactivity

Human

Immunogen

465-494 aa

Target

This UGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-494 amino acids from the C-terminal region of human UGDH.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

Summary

The protein encoded by this gene converts UDP-glucose toUDP-glucuronate and thereby participates in the biosynthesis ofglycosaminoglycans such as hyaluronan, chondroitin sulfate, andheparan sulfate. These glycosylated compounds are common componentsof the extracellular matrix and likely play roles in signaltransduction, cell migration, and cancer growth and metastasis. Theexpression of this gene is up-regulated by transforming growthfactor beta and down-regulated by hypoxia. Alternative splicingresults in multiple transcript variants.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH, UGDH

Images

UGDH Antibody (C-term) (Cat. APR10653G) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the UGDH antibody detected the UGDH protein (arrow).

UGDH Antibody (C-term) (Cat. APR10653G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of UGDH Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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