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ME2 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR08413G 100 μl / $495

ME2 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR08413G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ME2 antibody (C-term).

Molecular Weight

65444 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion matrix.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

527-556 aa

Target

This ME2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-556 amino acids from the C-terminal region of human ME2.

Isotype

Rabbit Ig

GeneID

UniProt ID

Summary

This gene encodes a mitochondrial NAD-dependent malicenzyme, a homotetrameric protein, that catalyzes the oxidativedecarboxylation of malate to pyruvate. It had previously beenweakly linked to a syndrome known as Friedreich ataxia that hassince been shown to be the result of mutation in a completelydifferent gene. Certain single-nucleotide polymorphism haplotypesof this gene have been shown to increase the risk for idiopathicgeneralized epilepsy. Alternatively spliced transcript variantsencoding different isoforms found for this gene. [provided byRefSeq].

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P, WB, E

Dilution

IHC-P~~1:10~50 WB~~1:1000

Synonyms

NAD-dependent malic enzyme, mitochondrial, NAD-ME, Malic enzyme 2, ME2

Images

ME2 Antibody (C-term) (Cat. APR08413G)immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ME2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

ME2 Antibody (C-term) (Cat. APR08413G) western blot analysis in mouse NIH-3T3,Neuro-2a cell line lysates (35ug/lane).This demonstrates the ME2 antibody detected the ME2 protein (arrow).

Specification

Quantity

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