> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > ME2 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR08413G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ME2 antibody (C-term).
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Molecular Weight |
65444 Da
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Cellular Localization |
Antigen Cellular Localization:
Mitochondrion matrix.
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
527-556 aa
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Target |
This ME2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-556 amino acids from the C-terminal region of human ME2.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Summary |
This gene encodes a mitochondrial NAD-dependent malicenzyme, a homotetrameric protein, that catalyzes the oxidativedecarboxylation of malate to pyruvate. It had previously beenweakly linked to a syndrome known as Friedreich ataxia that hassince been shown to be the result of mutation in a completelydifferent gene. Certain single-nucleotide polymorphism haplotypesof this gene have been shown to increase the risk for idiopathicgeneralized epilepsy. Alternatively spliced transcript variantsencoding different isoforms found for this gene. [provided byRefSeq].
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC-P, WB, E
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Dilution |
IHC-P~~1:10~50
WB~~1:1000
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Synonyms |
NAD-dependent malic enzyme, mitochondrial, NAD-ME, Malic enzyme 2, ME2
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Images |
ME2 Antibody (C-term) (Cat. APR08413G)immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ME2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
ME2 Antibody (C-term) (Cat. APR08413G) western blot analysis in mouse NIH-3T3,Neuro-2a cell line lysates (35ug/lane).This demonstrates the ME2 antibody detected the ME2 protein (arrow). |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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