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MLXIPL Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR08460G 100 μl / $495

MLXIPL Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR08460G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MLXIPL antibody (C-term).

Molecular Weight

93073 Da

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

624-653 aa

Target

This MLXIPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 624-653 amino acids from the C-terminal region of human MLXIPL.

Isotype

Rabbit Ig

Symbol

BHLHD14, MIO, WBSCR14

GeneID

UniProt ID

Function

Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3' (By similarity).

Summary

This gene encodes a basic helix-loop-helix leucine zippertranscription factor of the Myc/Max/Mad superfamily. This proteinforms a heterodimeric complex and binds and activates, in aglucose-dependent manner, carbohydrate response element (ChoRE)motifs in the promoters of triglyceride synthesis genes. The geneis deleted in Williams-Beuren syndrome, a multisystem developmentaldisorder caused by the deletion of contiguous genes at chromosome7q11.23.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Carbohydrate-responsive element-binding protein, ChREBP, Class D basic helix-loop-helix protein 14, bHLHd14, MLX interactor, MLX-interacting protein-like, WS basic-helix-loop-helix leucine zipper protein, WS-bHLH, Williams-Beuren syndrome chromosomal region 14 protein, MLXIPL, BHLHD14, MIO, WBSCR14

Images

All lanes : Anti-MLXIPL Antibody (C-term) at 1:2000 dilution Lane 1: Neuro-2a whole cell lysate Lane 2: SW620 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 93 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

All lanes : Anti-MLXIPL Antibody (C-term) at 1:2000 dilution Lane 1: K562 whole cell lysate Lane 2: NCI-H1299 whole cell lysate Lane 3: Neuro-2a whole cell lysate Lane 4: SW620 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 93 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

MLXIPL Antibody (C-term) (Cat. APR08460G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the MLXIPL antibody detected the MLXIPL protein (arrow).

Specification

Quantity

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