> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > RPGR Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR13146G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RPGR antibody (C-term).
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Molecular Weight |
113387 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q9R0X5}. Golgi apparatus
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
744-772 aa
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Target |
This RPGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744-772 amino acids from the C-terminal region of human RPGR.
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Isotype |
Rabbit Ig
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Symbol |
RP3, XLRP3
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GeneID |
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UniProt ID |
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Function |
Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes (By similarity). May be involved in microtubule organization and regulation of transport in primary cilia.
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Summary |
This gene encodes a protein with a series of six RCC1-likedomains (RLDs), characteristic of the highly conserved guaninenucleotide exchange factors. The encoded protein is found in theGolgi body and interacts with RPGRIP1. This protein localizes tothe outer segment of rod photoreceptors and is essential for theirviability. Mutations in this gene have been associated withX-linked retinitis pigmentosa (XLRP). Multiple alternativelyspliced transcript variants that encode different isoforms of thisgene have been reported, but the full-length natures of only somehave been determined.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
X-linked retinitis pigmentosa GTPase regulator, RPGR, RP3, XLRP3
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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