> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PDE1B Antibody (C-term)Brand |
Leading Biology | Catalog Number |
AMM07041G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PDE1B antibody (C-term).
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Molecular Weight |
61380 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm.
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
473-500 aa
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Target |
This PDE1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-500 amino acids from the C-terminal region of human PDE1B.
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Isotype |
Rabbit Ig
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Symbol |
PDE1B1, PDES1B
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GeneID |
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UniProt ID |
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Function |
Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate.
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Summary |
Cyclic nucleotide phosphodiesterases (PDEs) catalyzehydrolysis of the cyclic nucleotides cAMP and cGMP to thecorresponding nucleoside 5-prime-monophosphates. Mammalian PDEshave been classified into several families based on theirbiochemical properties. Members of the PDE1 family, such as PDE1B,are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that arestimulated by a calcium-calmodulin complex (Repaske et al., 1992[PubMed 1326532]).
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
Calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1B, Cam-PDE 1B, 63 kDa Cam-PDE, PDE1B, PDE1B1, PDES1B
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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