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STARD6 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR07190G 100 μl / $495

STARD6 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR07190G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality STARD6 antibody (C-term).

Molecular Weight

25022 Da

Host

Rabbit

Species Reactivity

Human

Immunogen

187-215 aa

Target

This STARD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-215 amino acids from the C-terminal region of human STARD6.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols (By similarity).

Summary

Cholesterol homeostasis is regulated, at least in part, bysterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM184756) and by liver X receptors (e.g., LXRA; MIM 602423). Uponsterol depletion, LXRs are inactive and SREBPs are cleaved, afterwhich they bind promoter SREs and activate genes involved incholesterol biosynthesis and uptake. Sterol transport is mediatedby vesicles or by soluble protein carriers, such as steroidogenicacute regulatory protein (STAR; MIM 600617). STAR is homologous toa family of proteins containing a 200- to 210-amino acidSTAR-related lipid transfer (START) domain, including STARD6(Soccio et al., 2002 [PubMed 12011452]).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1:1000 FC~~1:10~50

Synonyms

StAR-related lipid transfer protein 6, START domain-containing protein 6, StARD6, STARD6

Images

STARD6 Antibody (C-term) (Cat. APR07190G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the STARD6 antibody detected the STARD6 protein (arrow).

STARD6 Antibody (C-term) (Cat. APR07190G) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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