> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > GPD1L Antibody (N-term)Brand |
Leading Biology | Catalog Number |
AMM05181G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GPD1L antibody (N-term).
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Molecular Weight |
38419 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Note=Localized to the region of the plasma membrane
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
44-73 aa
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Target |
This GPD1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human GPD1L.
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Isotype |
Rabbit Ig
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Symbol |
KIAA0089
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GeneID |
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UniProt ID |
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Function |
Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L.
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Summary |
The protein encoded by this gene catalyzes the conversionof sn-glycerol 3-phosphate to glycerone phosphate. The encodedprotein is found in the cytoplasm, associated with the plasmamembrane, where it binds the sodium channel, voltage-gated, type V,alpha subunit (SCN5A). Defects in this gene are a cause of Brugadasyndrome type 2 (BRS2) as well as sudden infant death syndrome(SIDS).
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, FC, E
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Dilution |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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Synonyms |
Glycerol-3-phosphate dehydrogenase 1-like protein, GPD1-L, GPD1L, KIAA0089
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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