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AP3S1 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR14977G 100 μl / $495

AP3S1 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR14977G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AP3S1 antibody (N-term).

Molecular Weight

21732 Da

Cellular Localization

Antigen Cellular Localization: Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

1-30 aa

Target

This AP3S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human AP3S1.

Isotype

Rabbit Ig

Symbol

CLAPS3

GeneID

UniProt ID

Function

Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

Summary

Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Synonyms

AP-3 complex subunit sigma-1, AP-3 complex subunit sigma-3A, Adaptor-related protein complex 3 subunit sigma-1, Clathrin-associated/assembly/adaptor protein, small 3, Sigma-3A-adaptin, Sigma3A-adaptin, Sigma-adaptin 3a, AP3S1, CLAPS3

Images

AP3S1 Antibody (N-term) (Cat. APR14977G) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the AP3S1 antibody detected the AP3S1 protein (arrow).

AP3S1 Antibody (N-term) (Cat. APR14977G) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the AP3S1 antibody detected the AP3S1 protein (arrow).

AP3S1 antibody (N-term) (Cat. APR14977G) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the AP3S1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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