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PIP5K2B Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR10826G 100 μl / $545

PIP5K2B Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR10826G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PIP5K2B antibody (C-term).

Molecular Weight

47378 Da

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein Nucleus. Cytoplasm. Note=Associated with the plasma membrane and the endoplasmic reticulum.

Host

Rabbit

Species Reactivity

Human

Immunogen

286-317 aa

Target

This PIP5K2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-317 amino acids from the C-terminal region of human PIP5K2B.

Isotype

Rabbit Ig

Symbol

PIP5K2B

GeneID

UniProt ID

Function

Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.

Summary

PIP5K2B catalyzes the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-bisphosphate. It is a member of the phosphatidylinositol-4-phosphate 5-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Synonyms

Phosphatidylinositol 5-phosphate 4-kinase type-2 beta, 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta, Diphosphoinositide kinase 2-beta, Phosphatidylinositol 5-phosphate 4-kinase type II beta, PI(5)P 4-kinase type II beta, PIP4KII-beta, PtdIns(5)P-4-kinase isoform 2-beta, PIP4K2B, PIP5K2B

Images

The anti-PIP5K2B Pab (Cat. APR10826G) is used in Western blot to detect PIP5K2B in NCI-H460 cell lysate.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Specification

Quantity

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