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USP4 / UNP Antibody (N-Term)

Catalog # Availability Size / Price Inquiry
APG00412G 0.1mg / $495

USP4 / UNP Antibody (N-Term)

Brand

Leading Biology

Catalog Number

APG00412G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality USP4 / UNP Antibody (N-Term).

Molecular Weight

108565 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus Note=Shuttles between the nucleus and cytoplasm. Exported to the cytoplasm in a CRM1-dependent manner and recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor The relative amounts found in the nucleus and cytoplasm vary according to the cell type.

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

UNP, UNPH

GeneID

UniProt ID

Function

Hydrolase that deubiquitinates target proteins such as the receptor ADORA2A, PDPK1 and TRIM21. Deubiquitination of ADORA2A increases the amount of functional receptor at the cell surface. May regulate mRNA splicing through deubiquitination of the U4 spliceosomal protein PRPF3. This may prevent its recognition by the U5 component PRPF8 thereby destabilizing interactions within the U4/U6.U5 snRNP. May also play a role in the regulation of quality control in the ER.

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

Approx 100kDa band observed in Human Heart lysates (calculated MW of 104kDa according to NP_955475.1). Recommended concentration: 1-3 μg/ml.

Specification

Quantity

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