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TRIP / TRAIP Antibody (C-Term)

Catalog # Availability Size / Price Inquiry
APG00410G 0.1mg / $495

TRIP / TRAIP Antibody (C-Term)

Brand

Leading Biology

Catalog Number

APG00410G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TRIP / TRAIP Antibody (C-Term).

Molecular Weight

53294 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Cytoplasm, perinuclear region. Nucleus, nucleolus. Note=Occasionally observed at nuclear puncta

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

RNF206, TRIP

GeneID

UniProt ID

Function

Inhibits activation of NF-kappa-B mediated by TNF (By similarity). Negatively regulates TLR3/4- and RIG-I-mediated IRF3 activation and subsequent IFN-beta production and cellular antiviral response by promoting 'Lys-48'-linked polyubiquitination of TNK1 leading to its proteasomal degradation. May mediate assembly of 'Lys-63'-linked poly-ubiquitin chains on the Y-family polymerase POLN to facilitate bypass of DNA lesions and preserve genomic integrity.

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC, E

Images

Specification

Quantity

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