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PDGF-BB Antibody

Catalog # Availability Size / Price Inquiry
APR00412G 100 μg / $495

PDGF-BB Antibody

Brand

Leading Biology

Catalog Number

APR00412G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PDGF-BB Antibody.

Molecular Weight

27382 Da

Cellular Localization

Antigen Cellular Localization: Secreted. Note=Released by platelets upon wounding.

Host

Rabbit

Species Reactivity

Mouse

Target

PDGF-BB

Isotype

Rabbit IgG

Symbol

Sis

GeneID

UniProt ID

Function

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA.

Summary

Mouse Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF-BB is a 24.4.0 kDa protein containing 109 amino acid residues. The reduced form of PDGF-BB shows ~14-18 kDa on SDS-PAGE.

Form

100 μg (0.5 mg/ml) affinity purified rabbit anti-murine PDGF-BB polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% thimerosal

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Images

Western blot analysis using recombinat murine PDGF-BB. Lane1: 50ng; lane2: 250ng; lane3: 1ug.

Specification

Quantity

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