> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PDGF-BB AntibodyBrand |
Leading Biology | Catalog Number |
APR00412G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PDGF-BB Antibody.
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Molecular Weight |
27382 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted. Note=Released by platelets upon wounding.
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Host |
Rabbit
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Species Reactivity |
Mouse
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Target |
PDGF-BB
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Isotype |
Rabbit IgG
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Symbol |
Sis
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GeneID |
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UniProt ID |
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Function |
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA.
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Summary |
Mouse Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF-BB is a 24.4.0 kDa protein containing 109 amino acid residues. The reduced form of PDGF-BB shows ~14-18 kDa on SDS-PAGE.
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Form |
100 μg (0.5 mg/ml) affinity purified rabbit anti-murine PDGF-BB polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% thimerosal |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB
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Images |
Western blot analysis using recombinat murine PDGF-BB. Lane1: 50ng; lane2: 250ng; lane3: 1ug. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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