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TRAIL Antibody

Catalog # Availability Size / Price Inquiry
APR00410G 100 μg / $495

TRAIL Antibody

Brand

Leading Biology

Catalog Number

APR00410G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TRAIL Antibody.

Molecular Weight

32509 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type II membrane protein

Host

Rabbit

Species Reactivity

Human

Target

TRAIL

Isotype

Rabbit IgG

Symbol

APO2L, TRAIL

GeneID

UniProt ID

Function

Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.

Summary

Human TRAIL (TNF-Related Apoptosis Inducing Ligand), also called Apo2 Ligand (Apo2L), is a cytotoxic protein that activates rapid apoptosis in tumor cells, but not at normal cells. Human TRAIL/Apo2L is a single polypeptide chain containing 168 amino acids and has a molecular mass of 19.6 kDa.

Form

100 μg (0.5 mg/ml) affinity purified rabbit anti-human TRAIL polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5mM EDTA and 0.01% thimerosal.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Images

Western blot analysis using recombinant human TRAIL. Lane1: 50ng; Lane2: 100ng; Lane3: 200ng; Lane4: 500ng.

Specification

Quantity

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