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Perilipin A Antibody

Catalog # Availability Size / Price Inquiry
APR00233G 100 μg / $495

Perilipin A Antibody

Brand

Leading Biology

Catalog Number

APR00233G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Perilipin A Antibody.

Molecular Weight

55596 Da

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum. Lipid droplet. Note=Lipid droplet surface- associated

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

Perilipin A

Isotype

Rabbit IgG

Symbol

Peri, Plin

GeneID

UniProt ID

Function

Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone- sensitive lipase (HSL). Its absence may result in leanness (By similarity). Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels.

Summary

Perilipin is a protein produced and secreted by adipose cells. This protein is localized exclusively to the surface of lipid droplets. In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A. Once activated, perilipin has inhibitory effects on hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body. Perilipin expression is limited to adipocytes and steroidogenic cells.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Images

Western blot analysis of Perilipin A in Jurkat cell lysate.

Specification

Quantity

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