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LPL Antibody

Catalog # Availability Size / Price Inquiry
APR00232G 100 μg / $495

LPL Antibody

Brand

Leading Biology

Catalog Number

APR00232G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LPL Antibody.

Molecular Weight

53082 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Locates to the plasma membrane of microvilli of hepatocytes with triacyl- glycerol-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non-coated endocytic vesicles (By similarity).

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

LPL

Isotype

Rabbit IgG

GeneID

UniProt ID

Function

The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). Binding to heparin sulfate proteogylcans at the cell surface is vital to the function. The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the luminal surface of vascular endothelium (By similarity).

Summary

Lipoprotein lipase (LPL) is mainly expressed in the heart, muscle and adipose tissue. LPL is a homodimer that mediates the hydrolysis of triglycerides of very low density lipoproteins and also function as ligand/bridging factor for receptor-mediated lipoprotein uptake. Defects in LPL may result in hypertriglceridemia.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Images

Western blot analysis of LPL with lysate from rat kidney (Lane 1) and 3T3 cells (Lane 2).

Specification

Quantity

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