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GLUT4 Antibody

Catalog # Availability Size / Price Inquiry
APR00231G 100 μg / $495

GLUT4 Antibody

Brand

Leading Biology

Catalog Number

APR00231G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GLUT4 Antibody.

Molecular Weight

54755 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region Note=Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized. The dileucine internalization motif is critical for intracellular sequestration (By similarity).

Host

Rabbit

Species Reactivity

Mouse, Rat

Target

GLUT4

Isotype

Rabbit IgG

Symbol

Glut-4, Glut4

GeneID

UniProt ID

Function

Insulin-regulated facilitative glucose transporter.

Summary

Insulin stimulates glucose uptake in the muscles and adipose tissues by activating GLUT4 (Glucose Transporter Type 4). GLUT 4 is a transmembrane protein that facilitates glucose transport from storage sites to cell surface. Human insulin resistance involves a defect in GLUT4 that leads to accumulation in a dense membrane compartment from which insulin is unable to recruit GLUT4 to the cell surface.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Images

Specification

Quantity

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