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A1 Antibody

Catalog # Availability Size / Price Inquiry
APR00094G 100 μg / $495

A1 Antibody

Brand

Leading Biology

Catalog Number

APR00094G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality A1 Antibody.

Molecular Weight

20132 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

Bcl-2-related protein A1

Isotype

Rabbit IgG

Symbol

BCL2L5, BFL1, GRS, HBPA1

GeneID

UniProt ID

Function

Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity).

Summary

A1 (also designated Bfl-1) is a Bcl-2 family protein that dimerizes with both Bcl-2 and Bax, and has been identified as a hematopoietic-specific, early inducible gene. Altho μgh A1 demonstrated properties similar to those of Bcl-2, its function may be more temporally regulated during myeloid differentiation and is dependent on additional growth stimuli to confer its life promoting properties. A1 is abundantly expressed in bone marrow and at low levels in other tissues. A1 expression has been correlated to stomach cancer.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Images

Specification

Quantity

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