> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TFPI AntibodyBrand |
Leading Biology | Catalog Number |
APR00087G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TFPI Antibody.
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Molecular Weight |
35015 Da
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Cellular Localization |
Antigen Cellular Localization:
Isoform Alpha: Secreted.
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
TFPI
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Isotype |
Rabbit IgG
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Symbol |
LACI, TFPI1
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GeneID |
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UniProt ID |
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Function |
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
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Summary |
TFPI is also known as lipoprotein?associated coagulation inhibitor (LACI). TFPI encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates the formation of factor VIIa-TF complex, which proteolytically activates additional proteases and this leads to the formation of a fibrin clot. The encoded protein is glycosylated and primarily found in the vascular endothelium and plasma.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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