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CDC7 (CDC7L1) Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR05920G 100 μl / $495

CDC7 (CDC7L1) Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR05920G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDC7 (CDC7L1) Antibody (N-term).

Molecular Weight

63888 Da

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human

Immunogen

1-30 aa

Target

This CDC7 (CDC7L1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CDC7 (CDC7L1).

Isotype

Rabbit Ig

Symbol

CDC7L1

GeneID

UniProt ID

Function

Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.

Summary

CDC7L1 is predominantly localized in the nucleus and is a cell division cycle protein with kinase activity. Although expression levels of the protein appear to be constant throughout the cell cycle, the protein kinase activity appears to increase during S phase. It has been suggested that the protein is essential for initiation of DNA replication and that it plays a role in regulating cell cycle progression. Overexpression of this gene product may be associated with neoplastic transformation for some tumors.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

HCDC7L1 Antibody (M9) (Cat. APR05920G) western blot analysis in HT29,MCF-7 cell line lysates (35ug/lane).This demonstrates the HCDC7L1 antibody detected the HCDC7L1 protein (arrow).

HCDC7L1 Antibody (M9) (Cat. APR05920G) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the HCDC7L1 antibody detected the HCDC7L1 protein (arrow).

Specification

Quantity

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