> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > LZTS1 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR03772G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LZTS1 Antibody (N-term).
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Molecular Weight |
66613 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Cell membrane. Cell projection, dendritic spine Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse Note=Associated with the plasma membrane and with microtubules Detected in dendritic spines, especially in the postsynaptic density (By similarity).
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
77-105 aa
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Target |
This LZTS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-105 amino acids from the N-terminal region of human LZTS1.
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Isotype |
Rabbit Ig
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Symbol |
FEZ1
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GeneID |
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UniProt ID |
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Function |
Involved in the regulation of cell growth. May stabilize the active CDC2-cyclin B1 complex and thereby contribute to the regulation of the cell cycle and the prevention of uncontrolled cell proliferation. May act as a tumor suppressor.
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Summary |
This gene encodes a tumor suppressor protein that isubiquitously expressed in normal tissues. In uveal melanomas,expression of this protein is silenced in rapidly metastasizing andmetastatic tumor cells but has normal expression in slowlymetastasizing or nonmetastasizing tumor cells. This protein mayhave a role in cell-cycle control by interacting with theCdk1/cyclinB1 complex. This gene is located on chromosomal region8p22. Loss of heterozygosity (LOH) in the 8p arm is a commoncharacteristic of many types of cancer.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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