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K0776 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR06183G 100 μl / $495

K0776 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR06183G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality K0776 Antibody (Center).

Molecular Weight

89595 Da

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum. Cytoplasm, cytosol

Host

Rabbit

Species Reactivity

Human

Immunogen

426-455 aa

Target

This K0776 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-455 amino acids from the Central region of human K0776.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

E3 protein ligase that mediates ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, a post-translational modification on lysine residues of proteins that may play a crucial role in a number of cellular processes. Mediates DDRGK1 ufmylation and may regulate the proteasomal degradation of DDRGK1 and CDK5RAP3 thereby modulating NF-kappa-B signaling (PubMed:20018847, PubMed:20164180, PubMed:20228063, PubMed:25219498). May also through TRIP4 ufmylation play a role in nuclear receptors-mediated transcription (PubMed:25219498).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

Western blot analysis of K0776 Antibody (Center) (Cat. APR06183G) in MCF-7 cell line lysates (35ug/lane). K0776 (arrow) was detected using the purified Pab.

Specification

Quantity

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