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BCL11A Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR06182G 100 μl / $495

BCL11A Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR06182G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BCL11A Antibody (C-term).

Molecular Weight

91197 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Associates with the nuclear body. Colocalizes with SUMO1 and SENP2 in nuclear speckles (By similarity).

Host

Rabbit

Species Reactivity

Human

Immunogen

806-835 aa

Target

This BCL11A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 806-835 amino acids from the C-terminal region of human BCL11A.

Isotype

Rabbit Ig

Symbol

CTIP1, EVI9, KIAA1809, ZNF856

GeneID

UniProt ID

Function

Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1 (By similarity).

Summary

BCL11A is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

Western blot analysis of BCL11A Antibody (C-term) (Cat. APR06182G) in Jurkat, Ramos, 293, NCI-H460 cell line lysates (35ug/lane). BCL11A (arrow) was detected using the purified Pab.

Specification

Quantity

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