> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SEPSECS Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR04309G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SEPSECS Antibody (C-term).
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Molecular Weight |
55726 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
444-474 aa
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Target |
This SEPSECS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 444-474 amino acids from the C-terminal region of human SEPSECS.
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Isotype |
Rabbit Ig
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Symbol |
TRNP48
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GeneID |
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UniProt ID |
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Function |
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis.
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Summary |
The 21st amino acid, selenocysteine (sec), is distinctfrom other amino acids because it lacks its own tRNA synthetase andis the only amino acid synthesized on its cognate tRNA. Synthesisof sec begins with acylation of tRNA(sec) (TRSP; MIM 165060) byseryl-tRNA synthetase (SARS; MIM 607529) to give ser-tRNA(sec),which is subsequently phosphorylated by O-phosphoseryl-tRNA kinase(PSTK; MIM 611310) to give O-phosphoseryl-tRNA(sec). SEPSECScatalyzes the final step of sec synthesis by convertingO-phosphoseryl-tRNA(sec) to selenocysteinyl-tRNA(sec) usingselenophosphate as the selenium donor (Palioura et al., 2009[PubMed 19608919]).
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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