> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SLAMF6 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR04066G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SLAMF6 Antibody (C-term).
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Molecular Weight |
37345 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
277-305 aa
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Target |
This SLAMF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-305 amino acids from the C-terminal region of human SLAMF6.
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Isotype |
Rabbit Ig
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Symbol |
KALI
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GeneID |
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UniProt ID |
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Function |
Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors.
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Summary |
The protein encoded by this gene is a type I transmembraneprotein, belonging to the CD2 subfamily of the immunoglobulinsuperfamily. This encoded protein is expressed on Natural killer(NK), T, and B lymphocytes. It undergoes tyrosine phosphorylationand associates with the Src homology 2 domain-containing protein(SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs).It functions as a coreceptor in the process of NK cell activation.It can also mediate inhibitory signals in NK cells from X-linkedlymphoproliferative patients. Alternative splicing results inmultiple transcript variants encoding distinct isoforms.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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