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CD70 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR04006G 100 μl / $495

CD70 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR04006G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD70 Antibody (Center).

Molecular Weight

21118 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type II membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

72-101 aa

Target

This CD70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the Central region of human CD70.

Isotype

Rabbit Ig

Symbol

CD27L, CD27LG, TNFSF7

GeneID

UniProt ID

Function

Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.

Summary

The protein encoded by this gene is a cytokine thatbelongs to the tumor necrosis factor (TNF) ligand family. Thiscytokine is a ligand for TNFRSF27/CD27. It is a surface antigen onactivated, but not on resting, T and B lymphocytes. It inducesproliferation of costimulated T cells, enhances the generation ofcytolytic T cells, and contributes to T cell activation. Thiscytokine is also reported to play a role in regulating B-cellactivation, cytotoxic function of natural killer cells, andimmunoglobulin sythesis.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Images

CD70 Antibody (Center) (Cat. APR04006G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CD70 antibody detected the CD70 protein (arrow).

CD70 Antibody (Center) (APR04006G)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CD70 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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