> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CD70 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR04006G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CD70 Antibody (Center).
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Molecular Weight |
21118 Da
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Single-pass type II membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
72-101 aa
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Target |
This CD70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the Central region of human CD70.
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Isotype |
Rabbit Ig
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Symbol |
CD27L, CD27LG, TNFSF7
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GeneID |
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UniProt ID |
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Function |
Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
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Summary |
The protein encoded by this gene is a cytokine thatbelongs to the tumor necrosis factor (TNF) ligand family. Thiscytokine is a ligand for TNFRSF27/CD27. It is a surface antigen onactivated, but not on resting, T and B lymphocytes. It inducesproliferation of costimulated T cells, enhances the generation ofcytolytic T cells, and contributes to T cell activation. Thiscytokine is also reported to play a role in regulating B-cellactivation, cytotoxic function of natural killer cells, andimmunoglobulin sythesis.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Images |
CD70 Antibody (Center) (Cat. APR04006G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CD70 antibody detected the CD70 protein (arrow).
CD70 Antibody (Center) (APR04006G)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CD70 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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