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PSMA1 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR03980G 100 μl / $495

PSMA1 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR03980G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PSMA1 Antibody (C-term).

Molecular Weight

29556 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus.

Host

Rabbit

Species Reactivity

Human

Immunogen

234-262 aa

Target

This PSMA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-262 amino acids from the C-terminal region of human PSMA1.

Isotype

Rabbit Ig

Symbol

HC2, NU, PROS30, PSC2

GeneID

UniProt ID

Function

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal transduction in the macrophage proteasome (By similarity). Might be involved in the anti-inflammatory response of macrophages during the interaction with C.albicans heat-inactivated cells (By similarity).

Summary

The proteasome is a multicatalytic proteinase complex witha highly ordered ring-shaped 20S core structure. The core structureis composed of 4 rings of 28 non-identical subunits; 2 rings arecomposed of 7 alpha subunits and 2 rings are composed of 7 betasubunits. Proteasomes are distributed throughout eukaryotic cellsat a high concentration and cleave peptides in anATP/ubiquitin-dependent process in a non-lysosomal pathway. Anessential function of a modified proteasome, the immunoproteasome,is the processing of class I MHC peptides. This gene encodes amember of the peptidase T1A family, that is a 20S core alphasubunit. Alternative splicing results in multiple transcriptvariants encoding distinct isoforms.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

PSMA1 Antibody (C-term) (Cat. APR03980G) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PSMA1 antibody detected the PSMA1 protein (arrow).

Specification

Quantity

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