> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PHLDA2 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR03966G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PHLDA2 Antibody (C-term).
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Molecular Weight |
17092 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
90-119 aa
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Target |
This PHLDA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the C-terminal region of human PHLDA2.
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Isotype |
Rabbit Ig
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Symbol |
BWR1C, HLDA2, IPL, TSSC3
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GeneID |
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UniProt ID |
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Function |
Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity).
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Summary |
This gene is located in a cluster of imprinted genes onchromosome 11p15.5, which is considered to be an important tumorsuppressor gene region. Alterations in this region may beassociated with the Beckwith-Wiedemann syndrome, Wilms tumor,rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, andbreast cancer. This gene has been shown to be imprinted, withpreferential expression from the maternal allele in placenta andliver.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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