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GLMN Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR03649G 100 μl / $495

GLMN Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR03649G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GLMN Antibody (C-term).

Molecular Weight

68208 Da

Host

Rabbit

Species Reactivity

Human

Immunogen

498-525 aa

Target

This GLMN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-525 amino acids from the C-terminal region of human GLMN.

Isotype

Rabbit Ig

Symbol

FAP48, FAP68, VMGLOM

GeneID

UniProt ID

Function

Essential for normal development of the vasculature. May represent a naturally occurring ligand of the immunophilins FKBP59 and FKBP12. May function as an membrane anchoring protein. Isoform 1 may stimulate the p70S6K pathway. Isoform 2 may inhibit cell proliferation and increase IL2 production.

Summary

This gene encodes a phosphorylated protein that is amember of a Skp1-Cullin-F-box-like complex. The protein isessential for normal development of the vasculature and mutationsin this gene have been associated with glomuvenous malformations,also called glomangiomas. Alternatively spliced variants thatencode different protein isoforms have been described but thefull-length nature of only one has been determined. [provided byRefSeq].

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50

Images

GLMN Antibody (C-term) (Cat. APR03649G) western blot analysis in MDA-MB231,HepG2 cell line lysates (35ug/lane).This demonstrates the GLMN antibody detected the GLMN protein (arrow).

GLMN Antibody (C-term) (Cat. APR03649G)immunohistochemistry analysis in formalin fixed and paraffin embedded human bladder carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GLMN Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

GLMN Antibody (C-term) (Cat. APR03649G) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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