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MRM3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25604N-1 50ul / $395
APR25604N-2 100ul / $495
APR25604N-3 200ul / $595

MRM3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25604N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>RNA Binding

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MRM3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 47kDa Observed MW: 47kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human MRM3 (NP_060616.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G(1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

MRM3; RMTL1; RNMTL1; mitochondrial rRNA methyltransferase 3

Images

Western blot analysis of extracts of various cell lines, using MRM3 antibody.

Specification

Quantity

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