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DOCK2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25267N-1 50ul / $395
APR25267N-2 100ul / $495
APR25267N-3 200ul / $595

DOCK2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25267N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DOCK2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 38kDa/211kDa Observed MW: 240kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human DOCK2 (NP_004937.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:1000

Product Description

The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP.

Synonyms

DOCK2; IMD40; dedicator of cytokinesis 2

Images

Western blot analysis of extracts of Jurkat cells, using DOCK2 antibody.

Specification

Quantity

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