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TIE1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25212N-1 50ul / $395
APR25212N-2 100ul / $495
APR25212N-3 200ul / $595

TIE1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25212N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Growth factors

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TIE1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 34kDa/40kDa/125kDa Observed MW: 135/140kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human TIE1 (NP_005415.1).

Cross Reactivity

Human,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:200 - 1:2000

Product Description

This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms

TIE1; JTK14; TIE; tyrosine-protein kinase receptor Tie-1

Images

Western blot analysis of extracts of various cell lines, using TIE1 antibody.

Specification

Quantity

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