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UNC13D Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19738N-1 50ul / $395
APR19738N-2 100ul / $495
APR19738N-3 200ul / $595

UNC13D Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19738N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UNC13D Polyclonal Antibody.

Molecular Weight

Calculated MW: 41kDa/123kDa/128kDa Observed MW: 123kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human UNC13D (NP_954712.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:1000 - 1:2000

Product Description

This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

Synonyms

UNC13D; FHL3; HLH3; HPLH3; Munc13-4; unc-13 homolog D

Images

Western blot analysis of extracts of various cell lines, using UNC13D antibody.

Specification

Quantity

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