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A1CF Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19683N-1 50ul / $395
APR19683N-2 100ul / $495
APR19683N-3 200ul / $595

A1CF Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19683N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality A1CF Polyclonal Antibody.

Molecular Weight

Calculated MW: 55kDa/58kDa/62kDa/64kDa/65kDa Observed MW: 65kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human A1CF (NP_055391.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.

Synonyms

A1CF; ACF; ACF64; ACF65; APOBEC1CF; ASP; APOBEC1 complementation factor

Images

Western blot analysis of extracts of various cell lines, using A1CF antibody.

Specification

Quantity

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