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TJP3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19681N-1 50ul / $395
APR19681N-2 100ul / $495
APR19681N-3 200ul / $595

TJP3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19681N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TJP3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 97kDa/101kDa/102kDa/103kDa Observed MW: 150kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human TJP3 (NP_001254489.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1.

Synonyms

TJP3; ZO-3; ZO3; tight junction protein 3

Images

Western blot analysis of extracts of HeLa cells, using TJP3 antibody.

Specification

Quantity

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