> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SAG Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR19640N |
Product Type |
Polyclonal Antibodies | Field of Research |
Signal Transduction>G protein signaling |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SAG Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
45kDa
Observed MW:
48kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human SAG (NP_000532.2).
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Cross Reactivity |
Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC
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Dilution |
WB 1:1000 - 1:2000
IHC 1:50 - 1:200
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Product Description |
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness.
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Synonyms |
SAG; RP47; S-AG; S-arrestin
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Images |
Western blot analysis of extracts of various cell lines, using SAG antibody.
Immunohistochemistry of paraffin-embedded mouse retina using SAG antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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