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HNRNPH2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19589N-1 50ul / $395
APR19589N-2 100ul / $495
APR19589N-3 200ul / $595

HNRNPH2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19589N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>RNA Binding

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HNRNPH2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 49kDa Observed MW: 49kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human HNRNPH2 (NP_062543.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed.

Synonyms

HNRNPH2; FTP3; HNRPH'; HNRPH2; MRXSB; hnRNPH'; NRPH2; heterogeneous nuclear ribonucleoprotein H2

Images

Western blot analysis of extracts of HeLa cells, using HNRNPH2 antibody.

Immunofluorescence analysis of 293T cells using HNRNPH2 antibody.

Specification

Quantity

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