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MRPS31 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19539N-1 50ul / $395
APR19539N-2 100ul / $495
APR19539N-3 200ul / $595

MRPS31 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19539N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Mitochondrial metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MRPS31 Polyclonal Antibody.

Molecular Weight

Calculated MW: 45kDa Observed MW: 37kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human MRPS31 (NP_005821.2).

Cross Reactivity

Human,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:100 - 1:200

Product Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes; however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13.

Synonyms

MRPS31; IMOGN38; MRP-S31; S31mt; mitochondrial ribosomal protein S31

Images

Western blot analysis of extracts of various cell lines, using MRPS31 antibody.

Specification

Quantity

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