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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > [KO Validated] NDUFS2 Polyclonal Antibody

[KO Validated] NDUFS2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19471N-1 50ul / $395
APR19471N-2 100ul / $495
APR19471N-3 200ul / $595

[KO Validated] NDUFS2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19471N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Mitochondrial metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] NDUFS2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 51kDa/52kDa Observed MW: 49kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human NDUFS2 (NP_004541.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:1000 - 1:3000 IHC 1:50 - 1:200

Product Description

The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms

NDUFS2; CI-49; NADH:ubiquinone oxidoreductase core subunit S2

Images

Western blot analysis of extracts of various cell lines, using NDUFS2 antibody.

Western blot analysis of extracts from normal (control) and NDUFS2 knockout (KO) 293T cells, using NDUFS2 antibody.

Specification

Quantity

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