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SNX13 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19432N-1 50ul / $395
APR19432N-2 100ul / $495
APR19432N-3 200ul / $595

SNX13 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19432N

Product Type

Polyclonal Antibodies

Field of Research

Signal Transduction>G protein signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SNX13 Polyclonal Antibody.

Molecular Weight

Calculated MW: 110kDa/112kDa Observed MW: 112kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SNX13 (NP_055947.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.

Synonyms

SNX13; RGS-PX1; sorting nexin-13

Images

Western blot analysis of extracts of various cell lines, using SNX13 antibody.

Specification

Quantity

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