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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > [KO Validated] MAP2K1 Polyclonal Antibody

[KO Validated] MAP2K1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19312N-1 50ul / $395
APR19312N-2 100ul / $495
APR19312N-3 200ul / $595

[KO Validated] MAP2K1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19312N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] MAP2K1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 40kDa/43kDa Observed MW: 45kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human MAP2K1 (NP_002746.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:1000 - 1:3000 IHC 1:50 - 1:200

Product Description

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Synonyms

MAP2K1; CFC3; MAPKK1; MEK1; MKK1; PRKMK1; mitogen-activated protein kinase kinase 1

Images

Western blot analysis of extracts of various cell lines, using MAP2K1 antibody.

Western blot analysis of extracts from normal (control) and MAP2K1 knockout (KO) HeLa cells, using MAP2K1 antibody.

Specification

Quantity

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