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PEG3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19300N-1 50ul / $395
APR19300N-2 100ul / $495
APR19300N-3 200ul / $595

PEG3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19300N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PEG3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 60kDa/165kDa/166kDa/180kDa Observed MW: Refer to Figures

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PEG3 (NP_006201.1).

Cross Reactivity

Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.

Synonyms

PEG3; PW1; ZKSCAN22; ZNF904; ZSCAN24; paternally expressed 3

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Specification

Quantity

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