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BRWD1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19284N-1 50ul / $395
APR19284N-2 100ul / $495
APR19284N-3 200ul / $595

BRWD1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19284N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Chromatin Remodeling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BRWD1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 13kDa/248kDa/257kDa/262kDa Observed MW: 263kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human BRWD1 (NP_001007247.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:1000 - 1:3000

Product Description

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.

Synonyms

BRWD1; C21orf107; DCAF19; N143; WDR9; bromodomain and WD repeat domain containing 1

Images

Western blot analysis of extracts of various cell lines, using BRWD1 antibody.

Specification

Quantity

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