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PAFAH1B1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19270N-1 50ul / $395
APR19270N-2 100ul / $495
APR19270N-3 200ul / $595

PAFAH1B1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19270N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PAFAH1B1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 16kDa/46kDa Observed MW: 47kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PAFAH1B1 (NP_000421.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum.

Synonyms

PAFAH1B1; LIS1; LIS2; MDCR; MDS; NudF; PAFAH; platelet-activating factor acetylhydrolase IB subunit alpha

Images

Western blot analysis of extracts of various cell lines, using PAFAH1B1 antibody.

Specification

Quantity

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