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MAP3K7 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18724N-1 50ul / $395
APR18724N-2 100ul / $495
APR18724N-3 200ul / $595

MAP3K7 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18724N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MAP3K7 Polyclonal Antibody.

Molecular Weight

Calculated MW: 53kDa/56kDa/64kDa/67kDa Observed MW: 70kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human MAP3K7 (NP_003179.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Synonyms

MAP3K7; CSCF; FMD2; MEKK7; TAK1; TGF1a; mitogen-activated protein kinase kinase kinase 7

Images

Western blot analysis of extracts of various cell lines, using MAP3K7 antibody.

Specification

Quantity

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