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KLK6 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18697N-1 50ul / $395
APR18697N-2 100ul / $495
APR18697N-3 200ul / $595

KLK6 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18697N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Cell Type Marker

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KLK6 Polyclonal Antibody.

Molecular Weight

Calculated MW: 4kDa/15kDa/26kDa Observed MW: 27kDa

Species Reactivity

Rabbit

Immunogen

A synthetic synthetic peptide of human KLK6 (NP_002765.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a member of the kallikrein subfamily of the peptidase S1 family of serine proteases. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The encoded preproprotein is proteolytically processed to generate the mature protease. Expression of this protease is regulated by steroid hormones and may be elevated in multiple human cancers and in serum from psoriasis patients. The encoded protease may participate in the cleavage of amyloid precursor protein and alpha-synuclein, thus implicating this protease in Alzheimer's and Parkinson's disease, respectively. This gene is located in a gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Synonyms

KLK6; Bssp; Klk7; PRSS18; PRSS9; SP59; hK6; kallikrein-6

Images

Western blot analysis of extracts of various cell lines, using KLK6 antibody.

Specification

Quantity

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