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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > beta Catenin Polyclonal Antibody

beta Catenin Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18675N-1 50ul / $395
APR18675N-2 100ul / $495
APR18675N-3 200ul / $595

beta Catenin Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18675N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality beta Catenin Polyclonal Antibody.

Molecular Weight

Calculated MW: 9kDa/85kDa Observed MW: 100kDa

Species Reactivity

Rabbit

Immunogen

Recombinant protein of human beta Catenin

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF,IP

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100 IP 1:20 - 1:50

Product Description

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

Synonyms

CTNNB1; CTNNB; MRD19; armadillo; catenin beta-1

Images

Western blot analysis of extracts of various cell lines, using beta Catenin antibody.

Specification

Quantity

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