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GADD45A Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18638N-1 50ul / $395
APR18638N-2 100ul / $495
APR18638N-3 200ul / $595

GADD45A Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18638N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GADD45A Polyclonal Antibody.

Molecular Weight

Calculated MW: 14kDa/18kDa Observed MW: 20kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human GADD45A (NP_001915.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000

Product Description

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Synonyms

GADD45A; DDIT1; GADD45; growth arrest and DNA damage inducible alpha

Images

Western blot analysis of extracts of various cell lines, using GADD45A antibody.

Immunohistochemistry of paraffin-embedded rat lung using GADD45A antibody.

Immunohistochemistry of paraffin-embedded human thyroid cancer using GADD45A antibody.

Specification

Quantity

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