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CDC25A Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18615N-1 50ul / $395
APR18615N-2 100ul / $495
APR18615N-3 200ul / $595

CDC25A Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18615N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDC25A Polyclonal Antibody.

Molecular Weight

Calculated MW: 54kDa/59kDa Observed MW: 59kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CDC25A (NP_963861.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

CDC25A; CDC25A2; cell division cycle 25A

Images

Western blot analysis of extracts of various cell lines, using CDC25A antibody.

Immunohistochemistry of paraffin-embedded rat liver using CDC25A antibody.

Immunohistochemistry of paraffin-embedded human liver damage using CDC25A antibody.

Specification

Quantity

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